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Clostridium perfringens Type C Enterotoxemia.

L Niilo

    The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
    |August 1, 1988
    PubMed
    Summary
    This summary is machine-generated.

    Clostridium perfringens type C causes fatal enteric disease in many animal species and humans, particularly newborns. Vaccination of the dam is an effective control method for this toxemia.

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    Area of Science:

    • Veterinary Medicine
    • Microbiology
    • Animal Health

    Background:

    • Clostridium perfringens type C causes severe enteric disease in various animal species and humans.
    • Newborn animals exhibit heightened susceptibility due to factors like bacterial colonization and digestive functions.
    • The pathogenesis involves beta toxin and bacterial cell adherence to the jejunal villi, leading to necrotic mucosa.

    Purpose of the Study:

    • To critically review forms of enteric disease caused by Clostridium perfringens type C.
    • To emphasize practical aspects and recent research findings.
    • To highlight control strategies and potential research areas.

    Main Methods:

    • Review of available data and research findings.
    • Analysis of pathogenesis mechanisms.

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  • Assessment of control strategies.

    • Main Results:

    • Clostridium perfringens type C infects more animal species fatally than other types.
    • Fatal cases are documented in pigs, cattle, sheep, horses, and humans.
    • Death results from toxemia, despite intestinal lesions.

    Conclusions:

    • Clostridium perfringens type C infection is a significant threat to animal and human health.
    • Vaccination of the dam is an effective preventive measure.
    • Further research into the epizootiology of this disease is warranted.