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Relationship between Toxocara seropositivity and allergic rhinitis.
Murat Yariktas1, Mustafa Demirci, Giray Aynali
1Department of Otorhinolaryngology, Suleyman Demirel University School of Medicine, Isparta, Turkey. myariktas@hotmail.com
American Journal of Rhinology
|April 12, 2007
Summary
Toxocara infection may cause allergic rhinitis. Higher rates of Toxocara seropositivity were found in allergic rhinitis patients, suggesting a potential link between this parasitic infection and the chronic upper respiratory condition.
Area of Science:
- Immunology
- Parasitology
- Epidemiology
Background:
- Allergic rhinitis is a prevalent chronic upper respiratory disease.
- Improved diagnostic methods are needed for allergic rhinitis.
- The study explores the link between Toxocara infection and allergic rhinitis.
Purpose of the Study:
- To investigate the association between Toxocara seropositivity and allergic rhinitis.
- To determine if Toxocara infection is a risk factor for allergic rhinitis.
Main Methods:
- Included 64 allergic rhinitis patients and 61 healthy controls.
- Diagnosed allergic rhinitis via positive epicutaneous prick tests.
- Assessed Toxocara infection using ELISA for IgG and IgE antibodies.
Main Results:
- Toxocara seropositivity (IgG) was significantly higher in allergic rhinitis patients (28.1%) versus controls (11.5%).
- Specific IgE positivity was also elevated in allergic rhinitis patients (17.2%) compared to controls (3.3%).
Conclusions:
- A potential causal relationship exists between Toxocara infection and allergic rhinitis.
- Patients with allergic rhinitis in high-prevalence areas should be screened for Toxocara infection.
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