[Nutritional status of peritoneal dialysis patients and parameters of dialysis adequacy]

The aim of our study was to evaluate relations between peritoneal dialysis (PD) adequacy and nutritional parameters of PD patients. Patients (n = 124), who finished PD treatment, were separated on 2 groups according to the mean total Kt/V for the entire PD course being below 2.0 (group I) or over 2.0 (group II). Adequacy parameters, daily intake of food products and nutritional indices were evaluated in each patient every 3-6 months during the entire PD course. Mean values of examined parameters were used for comparison of differences observed between both groups. Group I included 63 men, 16 women, age 50.3 +/- 13.8 years, PD duration 13.2 +/- 10.1 months. Group II consisted of 12 men, 33 women, age 49.1 +/- 14.9 years, PD duration 8.8 +/- 6.0 months. Due to a significant difference in sex distribution, dialysis duration and ideal body mass (IBM) between groups, statistical analysis was performed with adjustment of results to these parameters. Absolute amounts of daily intake of food components were higher in group I for animal protein, sodium, retinol, niacin, saturated and polyunsaturated fatty acids and cholesterol. When daily food intake was normalized to IBM, group II showed higher both protein nitrogen appearance (I - 0.92 +/- 0.25, II - 1.12 +/- 0.45 g/kg IBM, p = 0.005) and intake of vegetable protein (I - 0.29 +/- 0.10, II - 0.34 +/- 0.09 g/kg IBM, p = 0.040), carbohydrates (I - 3.30 +/- 1.08, II - 3.80 +/- 1.34 g/kg IBM, p = 0.029), potassium (I - 33.2+/-10.6, II - 38.3 +/- 13.2 mg/kg IBM, p = 0.034), calcium (I - 5.81 +/- 2.46, II - 7.20 +/- 3.54 mg/kg IBM, p = 0.028), magnesium (I - 2.86 +/- 0.86, II - 3.41 +/- 1.36 mg/kg IBM, p = 0.004), beta-carotene (I 22.4 +/- 15.8, II - 34.9 +/- 29.1 mg/kg IBM, p = 0.002) as well as calorie delivered from protein (I - 0.22 +/- 0.04, II - 0.26 +/- 0.07%, p = 0.001) and carbohydrates (I - 0.79 +/- 0.15, II - 0.94 +/- 0.21, p = 0.000) in relation to total amount of ingested calorie. Group I showed significantly lower serum levels of albumin (I - 2.45, 1-3, II - 2.83, 1-3 scores, p = 0.023) and cholesterol (I - 5.54 +/- 1.06, II - 6.35 +/- 1.63 mmol/l, p = 0.009), but higher serum iron (I - 16.7 +/- 4.4, II - 15.8 +/- 5.2 micromol/l, p = 0.042) and ferritin (I - 615, 28-5113, II - 377, 24-3376 ng/ml, p = 0.021) concentrations as well as transferrin saturation (I - 31.1 +/- 9.2, II - 28.5 +/- 9.2%, p = 0.032). We conclude that PD patients with Kt/V over 2.0 as compared to those with Kt/V below 2.0 show tendency for better nutritional indices excluding serum iron parameters.