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Updated: Jul 15, 2026

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
[Vaccination in immunocompromised patients]
1Infektiologie, Universitätsspital Basel. weisserm@uhbs.ch
Abstract:
Vaccination strategies in immunocompromised patients differ from those in immunocompetent patients: The risk of severe and complicated infections is increased, the immune response to vaccination might be hampered and side-effects--especially vaccination-induced infections after live-vaccines--must carefully be weighed against benefit of vaccination. Encouragement of vaccination, adequate timing, boostering and newer immunological strategies can improve immunity. This article summarizes vaccination problems in patients with HIV/AIDS, Solid-organ transplantation, haematological stem cell transplantation, splenectomy and immunosuppressive drugs.
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