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Rifaximine versus neomycin in the treatment of portosystemic encephalopathy
S Di Piazza1, M Gabriella Filippazzo, L M Valenza
1Clinica Medica R Divisione di Medicina, Ospedale V Cervello, Universitì di Palermo, Italy.
The Italian Journal of Gastroenterology
|September 1, 1991
Abstract:
In 14 patients with cirrhosis and chronic portosystemic encephalopathy, the effectiveness of treatment with a new non-assorbable antibiotic (rifaximine) was compared to neomycin. The parameters evaluated were: bradylalia, flapping tremor, performance, visual evoked potentials and the trial making test. Both treatments were combined with lactulose. The analysis of results showed a rate of positive results in the patients treated with rifaximine greater than that with neomycin. Differences, however, were not significant.