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Updated: Jul 15, 2026

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Negative pressure wound therapy: treating a venomous insect bite.

Michael S Miller1, Marta Ortegon, Cheryl McDaniel

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Negative pressure wound therapy (NPWT) offers a novel treatment for severe spider bites, particularly those from the brown recluse spider. This case study demonstrates NPWT

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Area of Science:

  • Dermatology
  • Toxicology
  • Wound Healing

Background:

  • Brown recluse spider (Loxosceles reclusa) bites can cause severe cutaneous necrosis due to potent venom.
  • Limited research exists on using negative pressure wound therapy (NPWT) for spider bite treatment.
  • NPWT is recognized for its effectiveness in managing chronic, complex wounds.

Observation:

  • A patient presented with a non-healing upper arm wound suspected to be from a venomous spider bite.
  • The wound exhibited characteristics potentially linked to necrotizing spider venom.
  • Standard treatments may have been insufficient for this type of wound.

Findings:

  • Negative pressure wound therapy (NPWT) was successfully applied to treat the non-healing spider bite wound.
  • The patient's wound demonstrated significant improvement and healing under NPWT.
  • A novel, cost-effective NPWT system (Versatile 1) and drain (Miller DermiVex) were utilized.

Implications:

  • NPWT presents a viable therapeutic option for managing severe spider bite-induced cutaneous necrosis.
  • The successful use of new NPWT devices suggests potential for broader application in venomous bite wound care.
  • Further research into NPWT for venomous bites could establish new treatment protocols and improve patient outcomes.