The association between birth weight and visceral fat in middle-age adults

Marguerite J McNeely1, Wilfred Y Fujimoto, Donna L Leonetti

  • 1Department of Medicine, University of Washington, Division of General Internal Medicine, and Veterans Affairs Epidemiologic Research and Information Center, Veterans Affairs Puget Sound Health Care System, Seattle, 98105-4608, USA. mcneely@u.washington.edu

Insights

This study found no link between low birth weight and increased visceral fat in middle-aged adults. Further research is needed to understand the long-term health implications of birth weight.

Area of Science:

  • Endocrinology
  • Metabolic Health
  • Public Health

Background:

  • Low birth weight is a known risk factor for adult type 2 diabetes and central obesity.
  • The relationship between birth weight and visceral adiposity remains largely unexplored.

Purpose of the Study:

  • To investigate the association between lower birth weight and increased visceral fat in middle-aged adults.
  • To test the hypothesis linking reduced fetal development to greater intra-abdominal fat accumulation.

Main Methods:

  • Observational study of 91 adults (mean age 40 years).
  • Data collected on birth weight, BMI, smoking status, and visceral fat via computed tomography.
  • Participants were Japanese American or non-Hispanic white.

Main Results:

  • No significant association was found between birth weight and visceral fat after adjusting for age, sex, ethnicity, BMI, and smoking status (p=0.76).
  • The relationship between birth weight and visceral fat did not vary by age, sex, or ethnicity.

Conclusions:

  • This study found no evidence supporting a link between low birth weight and increased visceral fat in middle-aged adults.
  • The findings suggest that other factors may play a more significant role in visceral fat accumulation in adulthood.
Abstract

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