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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
The association between birth weight and visceral fat in middle-age adults
Marguerite J McNeely1, Wilfred Y Fujimoto, Donna L Leonetti
1Department of Medicine, University of Washington, Division of General Internal Medicine, and Veterans Affairs Epidemiologic Research and Information Center, Veterans Affairs Puget Sound Health Care System, Seattle, 98105-4608, USA. mcneely@u.washington.edu
Insights
This study found no link between low birth weight and increased visceral fat in middle-aged adults. Further research is needed to understand the long-term health implications of birth weight.
Area of Science:
- Endocrinology
- Metabolic Health
- Public Health
Background:
- Low birth weight is a known risk factor for adult type 2 diabetes and central obesity.
- The relationship between birth weight and visceral adiposity remains largely unexplored.
Purpose of the Study:
- To investigate the association between lower birth weight and increased visceral fat in middle-aged adults.
- To test the hypothesis linking reduced fetal development to greater intra-abdominal fat accumulation.
Main Methods:
- Observational study of 91 adults (mean age 40 years).
- Data collected on birth weight, BMI, smoking status, and visceral fat via computed tomography.
- Participants were Japanese American or non-Hispanic white.
Main Results:
- No significant association was found between birth weight and visceral fat after adjusting for age, sex, ethnicity, BMI, and smoking status (p=0.76).
- The relationship between birth weight and visceral fat did not vary by age, sex, or ethnicity.
Conclusions:
- This study found no evidence supporting a link between low birth weight and increased visceral fat in middle-aged adults.
- The findings suggest that other factors may play a more significant role in visceral fat accumulation in adulthood.
Objective:
Low birth weight, a proxy for fetal underdevelopment, is associated with increased risk of developing type 2 diabetes during adulthood. Low birth weight is also associated with central obesity, but little is known about the association between birth weight and visceral adiposity. The purpose of this study is to test the hypothesis that lower birth weight is associated with increased amounts of visceral fat in middle-age adults.
Research Methods And Procedures:
This is an observational study of 91 adults (58 men and 33 women) 40+/-6 years of age (mean+/-standard deviation). Ethnicity was either Japanese American (79%) or non-Hispanic white (21%). Birth weight was obtained from State Departments of Health. Measurements included smoking status, BMI, and visceral (intra-abdominal) fat measured by computed tomography.
Results:
Visceral fat was not associated with birth weight after adjustment for age, sex, ethnicity, BMI, or smoking status (p=0.76). There was no evidence that the association between birth weight and visceral fat varied by age, sex, or ethnicity.
Discussion:
We found no evidence that low birth weight is associated with increased visceral fat in middle-age adults.
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