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Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
Published on: September 19, 2018
Meeting report: tumor biology--how signaling processes translate to therapy
Karlheinz Friedrich1, Ottmar Janssen, Ralf Hass
1Institute of Biochemistry, Friedrich-Schiller University, Jena, Germany.
Abstract:
On the occasion of the 10th Joint Meeting "Signal Transduction-Receptors, Mediators and Genes" in November 2006, the Signal Transduction Society (STS) focused on the holy grail of translational research, that is, how basic signaling research might be transferred into cancer therapy. Participants heard of blockbusters and setbacks and learned of new therapeutic approaches that concentrate on distinct signaling pathways at a more individual level. Thus, the young STS community and the 300 meeting participants left with an optimistic outlook and the notion that the translational task will keep scientists busy all over the world for a while.
Insights
Basic signaling research holds promise for cancer therapy. The Signal Transduction Society (STS) meeting highlighted progress and challenges in translating basic science into effective cancer treatments, fostering optimism for future advancements.
Area of Science:
- Biomedical Sciences
- Molecular Biology
- Cancer Research
Background:
- The 10th Joint Meeting of the Signal Transduction Society (STS) convened in November 2006.
- The central theme was the critical challenge of translational research: bridging basic signaling science with clinical cancer therapy.
Framework:
- The meeting explored the transfer of fundamental discoveries in signal transduction pathways into tangible cancer treatments.
- Discussions encompassed both successful breakthroughs and significant obstacles encountered in this translational process.
Implementation:
- New therapeutic strategies targeting specific signaling pathways were presented.
- These approaches aim for a more personalized and individualized level of cancer treatment.
Implications:
- The event fostered an optimistic outlook within the Signal Transduction Society community.
- Translating signaling research into cancer therapy remains a vital and ongoing global scientific endeavor.
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