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Evidence of natural recombination in classical swine fever virus

Cheng-Qiang He1, Nai-Zheng Ding, Jian-Guo Chen

  • 1College of Life Science, Shandong Normal University, Jinan 250014, China. hchqiang@yahoo.com.cn

Virus Research
|April 13, 2007
PubMed

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
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