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Updated: Jul 15, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

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Gaze-contingent display for retinal function testing by scanning laser ophthalmoscope.

Manfred MacKeben¹, Alexander Gofen

¹The Smith-Kettlewell Eye Research Institute, San Francisco, CA 94115, USA. mm@ski.org

Journal of the Optical Society of America. A, Optics, Image Science, and Vision

|April 13, 2007

Summary

A new smart microperimetry program enhances scanning laser ophthalmoscope (SLO) use by processing retinal images in real-time. This improves the efficiency and precision of visual field testing, overcoming limitations of older software.

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Area of Science:

Ophthalmology
Medical Imaging
Computational Neuroscience

Background:

Conventional microperimetry software using scanning laser ophthalmoscope (SLO) in clinical settings presents challenges related to inconvenience and imprecision.
Involuntary eye movements and image quality fluctuations can compromise the accuracy of traditional visual field testing.

Purpose of the Study:

To develop and evaluate a "smart microperimetry" program designed to enhance the precision and efficiency of microperimetry using SLO.
To leverage modern computer technology for real-time image processing and stimulus placement correction during SLO-based visual field testing.

Main Methods:

Development of a "smart microperimetry" software utilizing advanced processing speed and data transfer capabilities.
Implementation of continuous on-line retinal image processing for instantaneous correction of stimulus placement based on involuntary eye movements.

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Integration of gaze-contingent display and image tracking to prevent stimulation during blinks or poor image quality.

Main Results:

The smart microperimetry program enables continuous, real-time processing of retinal images.
Instantaneous correction of stimulus placement compensates for involuntary eye movements, ensuring accurate gaze-contingent display.
The system effectively prevents stimulation during undesirable events like blinks or periods of flawed image quality.

Conclusions:

The developed smart microperimetry program significantly increases the efficiency and precision of scanning laser ophthalmoscope data acquisition.
This novel approach overcomes the limitations of conventional software, offering a more reliable method for clinical microperimetry.
The advancements in real-time processing and gaze-contingent stimulus delivery represent a substantial improvement in visual field testing technology.