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Updated: Jul 15, 2026
Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
Published on: August 28, 2015
Cell migration rate on poly(epsilon-caprolactone)/poly(ethylene glycol) diblock copolymers and correlation with the
Shan-hui Hsu1, Cheng-Ming Tang, Jeng-Jiann Chiu
1Center of Tissue Engineering and Stem Cells Research, National Chung Hsing University, Taichung, Taiwan, Republic of China. shhsu@nchu.edu.tw
Abstract:
The nanostructure of a biomaterial surface has strong influence on cell behavior. The migration of cells on nanostructured surfaces, however, has not been investigated so far. In this study, we used PCL/PEG diblock copolymers as model surfaces to examine the effect of nanoislands on migration of different cells, including fibroblasts and endothelial cells. The water sliding angle of the substrates was measured. The cell migration rate was examined under a real-time optical microscope. It was found that a greater cell migration rate correlated with the smaller sliding angle of the substrate.
