Formulation of transdermal drug delivery system: matrix type, and selection of polymer- their evaluation

Rajesh Kaza1, R Pitchaimani

  • 1Sree Vidyanikethan, College of Pharmacy, Sree Sainath Nagar, A Rangampet-517102, Chandragiri Mandal, Chittoor Dt, AP, India. rajeshkaza5@yahoo.co.in

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Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...
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