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Published on: March 29, 2022
Paediatric pseudophakia: analysis of intraocular lens power and myopic shift
William F Astle1, April D Ingram, Gloria M Isaza
1The Alberta Children's Hospital, University of Calgary, Division of Ophthalmology, Calgary, Alberta, Canada. william.astle@calgaryhealthregion.ca
Insights
Young children undergoing cataract surgery experience significant myopic shift, especially those under 4 years old. Adjusting intraocular lens (IOL) power based on age and fellow eye refraction is crucial for optimal outcomes in pediatric cataract patients.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Biomedical Engineering
Background:
- Paediatric cataract extraction with intraocular lens (IOL) implantation has been performed for over 10 years.
- Evaluating the success of predicting IOL power requires understanding myopic shift in different pediatric age groups and cataract types.
Purpose of the Study:
- To examine the amount of myopic shift in various pediatric age groups after cataract surgery.
- To assess the success of predicting appropriate intraocular lens (IOL) power for pediatric patients.
Main Methods:
- Retrospective review of 163 eyes from 126 patients (1 month to 18 years) undergoing small incision posterior chamber foldable IOL implantation (1995-2005).
- Patients were followed for at least 6 months postoperatively.
- Children were divided into four age groups at the time of surgery: 1-24 months, 25-48 months, 49-84 months, and 85 months-18 years.
Main Results:
- Children under 4 years experienced the most significant myopic shift (mean change: Group A -5.43 D, Group B -4.16 D).
- The mean rate of refractive change per year was highest in the youngest age groups.
- 89% of unilateral cataract patients had postoperative refraction within 3.00 D of the fellow eye.
Conclusions:
- A high rate of myopic shift occurs in children under 4 years old, potentially reaching -12.00 D.
- Mean postoperative target refraction recommendations may need to be increased.
- Patient age at surgery and fellow eye refractive power are critical factors for IOL power selection in pediatric cataract cases.
Background:
At the Alberta Children's Hospital, the authors have been performing paediatric cataract extraction with intraocular lens (IOL) implant for over 10 years. The authors examined the amount of myopic shift that occurs in various age groups and cataract types, in order to evaluate the success of predicting the appropriate power of IOL to implant.
Methods:
This study is a retrospective review children undergoing small incision posterior chamber foldable IOL implantation between age 1 month and 18 years, from 1995 to 2005. 163 eyes of 126 patients underwent surgery. All patients were followed for a minimum of 6 months postoperatively. The children were divided into four groups at time of surgery: Group A: 1-24 months, Group B: 25-48 months, Group C: 49-84 months, Group D: 85 months-18 years.
Results:
The mean target refraction for the groups were: Group A: +6.37 D, Group B: +4.66 D, Group C: +1.95 D, and Group D: +0.97 D. Children under 4 years experienced the most myopic shift and the largest mean rate of refractive change per year. Mean change Group A: -5.43 D, Group B: -4.16 D, Group C: -1.58 D, Group D: -0.71 D. Eighty-nine per cent of patients with unilateral cataracts had a postoperative refraction within 3.00 D of the fellow eye at last follow-up visit (mean=3.16 years).
Conclusions:
The rate of myopic shift is high in children under age 4 years at time of surgery, shifting as much as -12.00 D. The mean postoperative target refraction should probably be increased from previous literature recommendations. The patient's age at time of cataract surgery and the refractive power of fellow eye are all factors to consider when deciding what power IOL to surgically implant in a paediatric patient.
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