Selection responses for disease resistance in two selection experiments with Norwegian red cows

Genetic trends for clinical mastitis (CM), ketosis (KET), retained placenta (RP), and 305-d protein yield (PY305) were calculated for 2 Norwegian dairy cattle selection experiments. The first experiment, accomplished from 1978 to 1989, included groups selected for high (HMP) and low milk production (LMP). The second experiment started in 1989 and included selection for high protein yield (HPY) and low mastitis frequency (LCM). In both experiments proven sires from the active breeding program of Norwegian Red were used as sires. To take into account that selection of sires was external to the experiment, all available data from the Norwegian Red population, including disease records for 2.7 million first-lactation cows, were analyzed with a multivariate animal model. Estimated breeding values for cows in the experiments were extracted from this analysis to calculate genetic trends in the selection groups. Genetic trends for PY305 were, as expected, positive for the HMP and HPY groups, and negative for LMP and LCM. The HMP group showed increasing genetic trends for all 3 diseases, arguably a correlated response after selection for increased milk production, whereas the LCM group showed decreasing genetic trends for CM, KET, and RP. The genetic trends for KET and RP in the LCM group are most likely correlated responses after selection against CM. After 5 cow-generations the genetic difference between HPY and LCM was 10 percentage units CM, 1.5 percentage units KET, and 0.5 percentage units RP.