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Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Corrigendum to "Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer": [Ann Oncol 36 (2025) 76-88].

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Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer.

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Fragmentomic analysis of circulating tumor DNA-targeted cancer panels.

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Clinical trials for metastatic castrate-resistant prostate cancer-who is looking after the control patients? Questions for the future.

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Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer.

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Related Experiment Video

Updated: Jul 15, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Systemic strategies for prostate cancer.

A J Armstrong1, P G Febbo, D J George

  • 1Duke Prostate Center, Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, USA. andrew.armstrong@duke.edu

Minerva Urologica E Nefrologica = the Italian Journal of Urology and Nephrology
|April 14, 2007
PubMed
Summary

Systemic therapies beyond hormonal therapy are crucial for advanced prostate cancer. Research is evaluating chemotherapy and other agents in early and late disease stages to improve cure rates.

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Area of Science:

  • Urologic Oncology
  • Medical Oncology

Background:

  • Hormonal therapy is standard for advanced prostate cancer.
  • Systemic therapies including chemotherapy are gaining acceptance for hormone-refractory disease.

Purpose of the Study:

  • To review the state of systemic therapy for advanced prostate cancer in 2007.
  • To emphasize agents in phase II and III trials impacting the standard of care.

Main Methods:

  • Review of current systemic therapies for advanced prostate cancer.
  • Emphasis on neoadjuvant, adjuvant, and metastatic settings.
  • Focus on agents in ongoing phase II and III clinical trials.

Main Results:

  • Chemotherapy acceptance is increasing for hormone-refractory prostate cancer.
  • Ongoing trials aim to define the role of systemic therapy in earlier disease states.
  • Biomarker identification is crucial for predicting treatment sensitivity.

Conclusions:

  • Systemic therapies beyond hormonal therapy hold promise for advanced prostate cancer.
  • Clinical trials are essential for advancing prostate cancer management.
  • Personalized treatment approaches based on biomarkers are anticipated.