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Preparation of magnetite nanocrystals with surface reactive moieties by one-pot reaction
Fengqin Hu1, Zhen Li, Chifeng Tu
1Key Laboratory of Colloid, Interface Science and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Zhong Guan Cun, Bei Yi Jie 2, Beijing 100080, China.
Abstract:
By one-pot reaction, biocompatible magnetite nanocrystals with surface reactive moieties were prepared through the thermal decomposition of Fe(acac)(3) in 2-pyrrolidone using alpha,omega-dicarboxyl-terminated poly(ethylene glycol) as surface capping molecule. The successful conjugation between the magnetite nanocrystals and 9-amino acridine on the one hand demonstrates the existence of free carboxylic groups from PEG binding on the particle surface, on the other hand may also lead to a new type of magneto-optical materials as well as magneto-drugs.
