Related Experiment Video

Updated: Jul 15, 2026

A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines
06:59

A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines

Published on: June 22, 2022

CFTR stabilizes ENaC at the plasma membrane

C Lu1, C Jiang, S Pribanic

  • 1Program in Cell Biology, The Hospital for Sick Children, and Biochemistry Department, University of Toronto, 555 University Ave, Toronto, Ontario, Canada M5G 1X8.

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
|April 17, 2007
PubMed
Summary

Cystic fibrosis transmembrane conductance regulator (CFTR) surprisingly stabilizes epithelial sodium channel (ENaC) at the cell surface. This suggests CFTR impacts ENaC stability rather than just its opening.

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