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Bone formation markers in adults with mild osteogenesis imperfecta

Tim Cundy1, Anne Horne, Mark Bolland

  • 1Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. t.cundy@auckland.ac.nz

Clinical Chemistry
|April 17, 2007
PubMed
Summary

The osteocalcin to procollagen-1 N-peptide (P1NP) ratio effectively diagnoses type I osteogenesis imperfecta (OI) in adults. This bone marker combination shows high sensitivity and specificity for differentiating type I OI from other conditions.

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