Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Salivary response to training in young professional football players.

British dental journal·2026
Same author

Exploring the Correlation between Salivary Spinnbarkeit and Caries Scores.

Caries research·2024
Same author

The consistent application of hydrogen peroxide controls biofilm growth and removes <i>Vermamoeba vermiformis</i> from multi-kingdom <i>in-vitro</i> dental unit water biofilms.

Biofilm·2023
Same author

GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1.

International journal of oral science·2022
Same author

The Highly Leukotoxic JP2 Genotype of <i>Aggregatibacter actinomycetemcomitans</i> Is Present in the Population of the West African Island, Sal in Cape Verde: A Pilot Study.

Pathogens (Basel, Switzerland)·2022
Same author

Niacin Limitation Promotes <i>Candida glabrata</i> Adhesion to Abiotic Surfaces.

Pathogens (Basel, Switzerland)·2022

Related Experiment Video

Updated: Jul 15, 2026

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
09:44

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy

Published on: October 20, 2011

Oral diseases: from detection to diagnostics.

Antoon J M Ligtenberg1, Johannes J de Soet, Enno C I Veerman

  • 1Department of Oral Biochemistry, Academic Centre for Dentistry, Amsterdam, the Netherlands. ajm.ligtenberg@vumc.nl

Annals of the New York Academy of Sciences
|April 17, 2007
PubMed
Summary

Objective diagnostic tests for oral diseases like caries are needed. Saliva

Area of Science:

  • Oral diagnostics
  • Biomarkers
  • Proteomics

Background:

  • Visual diagnosis for caries and periodontal disease is common but lacks predictive value.
  • Objective diagnostic tests are desired for better oral disease prediction.
  • Existing models like Cariogram incorporate saliva factors, but correlations are not fully conclusive.

Purpose of the Study:

  • To explore the diagnostic potential of various oral components beyond saliva.
  • To investigate functional aspects of saliva, like bacterial aggregation, for caries prediction.
  • To leverage modern proteomic techniques for comprehensive analysis of salivary functions.

Main Methods:

  • Analysis of oral components including saliva, gingival crevicular fluid, and dental plaque.
  • Review of correlation studies on salivary components and caries.

More Related Videos

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
11:15

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA

Published on: May 21, 2015

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Related Experiment Videos

Last Updated: Jul 15, 2026

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
09:44

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy

Published on: October 20, 2011

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
11:15

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA

Published on: May 21, 2015

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

  • Application of modern proteomic techniques to study salivary functions.

    • Main Results:

    • Saliva, gingival crevicular fluid, and other oral samples show diagnostic potential.
    • Functional aspects of saliva, such as bacterial aggregation, show promising correlations with caries.
    • Proteomic techniques enable simultaneous study of multiple salivary components.

    Conclusions:

    • Objective diagnostic tools for oral diseases are crucial.
    • Functional salivary analysis, particularly bacterial aggregation, offers a promising avenue for caries prediction.
    • Proteomics can advance the understanding of salivary roles in oral health and disease.