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Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
Outdoor air pollution: ozone health effects
Tze-Ming Chen1, Janaki Gokhale, Scott Shofer
1Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Stanford, California, USA.
Abstract:
Ozone is a respiratory irritant associated with a spectrum of adverse health events. Ground-level ozone has been shown to cause decreases in lung function and has been associated with other important respiratory health effects. Some reports suggest short-term increases in ozone lead to increased cardiopulmonary mortality. Other studies have found no association between exposure and measured health effects. Outdoor air pollution consists of multiple copollutant exposures complicating definitive assessments about ambient air ozone exposure-effect relations.
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