Related Experiment Video
Updated: Jul 15, 2026

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice
Published on: July 5, 2024
Ovarian stimulation in polycystic ovarian syndrome
1Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel.
Abstract:
We tried to overview the various methods of ovulation induction in patients with polycystic ovarian syndrome (PCOS), a syndrome that remains a diagnostic and therapeutic challenge. Although fertility treatments have been given since the early 1960s, there is controversy and a long-standing debate on the treatment of choice in these patients, taking into consideration the success rates and possible complications. Clomiphene citrate (CC) is still the first drug of choice, but new medications, such as metformin and aromatase inhibitor, and new protocols like the chromic low dose, are suggested as better alternatives to CC treatment. To reach such a conclusion, more prospective randomized control trials should be done. Because PCOS contains a verity of fertility and general health problems and symptoms, it is of great importance to "tailor" the specific treatment to the individual patient.
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