Changes in plasma phenytoin level following craniotomy

J S Yeh1, J S Dhir, A L Green

  • 1Department of Neurosurgery, University Hospital of North Staffordshire, Stoke-on-Trent, UK.

Summary

Plasma phenytoin levels often drop after craniotomy, potentially increasing seizure risk. This study tracked phenytoin concentrations in patients undergoing brain surgery, finding significant decreases post-operation that may impact treatment effectiveness.

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