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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...

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Related Experiment Video

Updated: Jul 15, 2026

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

Nanotechnology applications in cancer.

Shuming Nie1, Yun Xing, Gloria J Kim

  • 1Department of Biomedical Engineering and the Winship Cancer Institute, Emory University and Georgia Institute of Technology, Atlanta, Georgia 30322, USA. snie@emory.edu

Annual Review of Biomedical Engineering
|April 19, 2007
PubMed
Summary

Cancer nanotechnology utilizes nanoparticles for advanced molecular imaging, diagnosis, and targeted cancer therapy. These nanomedicine approaches enable personalized oncology by leveraging individual patient biomarkers for precise treatment.

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Area of Science:

  • Interdisciplinary research spanning science, engineering, and medicine.
  • Focus on nanometer-sized particles for advanced biomedical applications.

Background:

  • Nanoparticles possess unique optical, magnetic, and structural properties distinct from bulk materials.
  • These properties are harnessed for cancer molecular imaging, diagnosis, and targeted therapy.

Purpose of the Study:

  • To explore the applications of cancer nanotechnology in diagnostics and therapeutics.
  • To highlight the potential of nanoparticles for targeted cancer treatment and early detection.

Main Methods:

  • Utilizing nanoparticles (e.g., quantum dots, iron oxide nanocrystals) functionalized with tumor-targeting ligands.
  • Conjugating diagnostic and therapeutic agents to nanoparticles for enhanced efficacy.
  • Developing bioaffinity nanoparticle probes for molecular and cellular imaging.

Main Results:

  • Nanoparticles demonstrate high affinity and specificity for targeting tumor antigens and vasculature.
  • Successful development of targeted nanoparticle drugs for cancer therapy.
  • Creation of integrated nanodevices for early cancer detection and screening.

Conclusions:

  • Cancer nanotechnology offers significant advancements in cancer diagnosis and treatment.
  • These nanomedicine strategies pave the way for personalized oncology based on individual molecular profiles.