Related Experiment Video
Updated: Aug 6, 2026

Preparation and Maintenance of Dorsal Root Ganglia Neurons in Compartmented Cultures
Published on: October 17, 2008
Considerations on neurotrophic relations in the central and peripheral nervous system
Neurotrophic influences, crucial for cell communication, involve growth processes similar in both central and peripheral nervous systems. Understanding these mechanisms is key to addressing neuronal changes.
Area of Science:
- Neuroscience
- Cell Biology
- Neurobiology
Background:
- Non-impulse mediated intercellular communication, termed neurotrophic influences, plays a significant role in neuronal function.
- Differentiating neurotrophic influences from other intercellular mechanisms requires careful selection of experimental parameters.
- Growth processes are central to neurotrophic control, exhibiting similarities across the central and peripheral nervous systems.
Purpose of the Study:
- To review the evidence for neurotrophic influences.
- To emphasize the importance of growth processes in neurotrophic control.
- To discuss phenomena indicating mechanisms of growth and growth arrest in neurotrophic control.
Main Methods:
- Literature review focusing on neurotrophic influences.
- Analysis of parameters for differentiating neurotrophic effects.
- Examination of cellular phenomena related to growth and arrest.
Main Results:
- Evidence supports the existence of neurotrophic influences.
- Growth mechanisms in neurotrophic control appear conserved between central and peripheral nervous systems.
- Collateral sprouting and "silent" synapses/terminals exemplify growth and arrest phenomena.
Conclusions:
- Neurotrophic influences are a vital aspect of intercellular communication.
- Growth and arrest processes are fundamental to neurotrophic control.
- Understanding these mechanisms is crucial for addressing age-related neuronal changes and synaptic dysfunction.
More Related Videos
15:05Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons
Published on: February 5, 2015
10:45Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
Published on: May 31, 2017
Related Concept Videos
What is a Nervous System?
Glial Cells
Organization of the Nervous System
The CNS, comprising the brain and spinal cord, houses billions of neurons. The brain is housed in the skull, while the spinal cord is linked to the brain through the foramen magnum of the occipital bone and is surrounded by the protective structure of the vertebral column. It is responsible for processing various...
Neurogenesis and Regeneration of Nervous Tissue
Peripheral Nervous System: Ganglia and Nerves
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
Nervous System
Extending...