Related Experiment Video

Updated: Jul 15, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Epidemiology of familial multiple sclerosis in Hungary

Z Fricska-Nagy1, K Bencsik, C Rajda

  • 1Department of Neurology, Albert Szent-Gyögyi Medical and Pharmaceutical Centre, University of Szeged, Hungary.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|April 19, 2007
PubMed

Insights

Familial multiple sclerosis (MS) risk in Hungary appears lower than previously estimated, suggesting unique genetic or environmental factors. This study provides the first data on familial MS prevalence in Hungary and Eastern Europe.

Area of Science:

  • Neurology
  • Genetics
  • Epidemiology

Background:

  • Familial aggregation of multiple sclerosis (MS) is estimated at 5-10%, with genetic factors often emphasized over environmental influences.
  • Existing literature lacks specific data on familial MS prevalence in Hungary and the broader Middle Eastern Europe region.

Purpose of the Study:

  • To investigate the prevalence and familial accumulation of multiple sclerosis (MS) within Hungary.
  • To provide the first epidemiological data on familial MS in Hungary and compare it with international findings.

Main Methods:

  • A retrospective study involving 1500 patients diagnosed with MS across five Hungarian MS centers.
  • Analysis of familial aggregation patterns within the studied patient cohort.

Main Results:

  • The prevalence of familial MS in Hungary was found to be lower than the 5-10% estimated in international studies.
  • This research presents the initial data on familial MS prevalence specifically for Hungary and Middle Eastern Europe.

Conclusions:

  • The risk of familial multiple sclerosis in Hungary may be lower than in other documented regions.
  • Further research is needed to understand the specific genetic and environmental factors contributing to MS in this population.

More Related Videos

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...