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Published on: April 5, 2019
Clinical and laboratory features of neuromyelitis optica with oligoclonal IgG bands
M Nakamura1, I Nakashima, S Sato
1Department of Neurology, Tohoku University School of Medicine, Aoba-ku, Sendai 980-8574, Japan. mnakamura@em.neurol.med.tohoku.ac.jp
Abstract:
Of 23 neuromyelitis optica (NMO) cases, we found two cases with oligoclonal IgG bands (OBs). Both patients were positive for NMO-IgG. Their common features were long disease duration and co-existing autoimmune diseases (myasthenia gravis and sicca syndrome). Although OBs are mostly negative in NMO, which distinguishes it from multiple sclerosis (MS), they can be positive by long-standing autoimmunity, which may not be directly related to NMO.
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