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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: Jul 15, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
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State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

Evaluation of normal brain development by prenatal MR imaging.

L Manganaro1, A Perrone, S Savelli

  • 1Dipartimento di Scienze Radiologiche, Università degli studi di Roma La Sapienza, Via Regina Elena 324, I-00161 Rome, Italy.

La Radiologia Medica
|April 19, 2007
PubMed
Summary

Magnetic resonance imaging (MRI) reliably assesses fetal brain development. This study correlates MRI findings with gestational age, detailing normal maturation patterns and key developmental milestones.

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Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function
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Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function

Published on: March 10, 2026

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Last Updated: Jul 15, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
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Published on: February 2, 2015

Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function
07:31

Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function

Published on: March 10, 2026

Area of Science:

  • Neuroimaging
  • Developmental Biology
  • Radiology

Background:

  • Fetal brain development is a complex process.
  • Accurate assessment of fetal brain maturation is crucial for prenatal care.
  • Magnetic Resonance Imaging (MRI) offers advanced visualization capabilities for in-utero assessment.

Purpose of the Study:

  • To describe normal fetal brain development and maturation patterns in relation to gestational age using MRI.
  • To evaluate the utility of MRI techniques in assessing fetal brain development.
  • To correlate specific fetal brain structures and diffusion parameters with gestational age.

Main Methods:

  • Fetal cerebral MRI was performed on 56 pregnant women (19-37 weeks gestation).
  • Utilized various MRI sequences including HASTE, FISP, FLASH, and diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping.
  • Correlated biometric parameters and cerebral cortex development with gestational age using Spearman rank correlation.

Main Results:

  • Established correlations between germinal matrix/biparietal diameter ratio and gestational age.
  • Demonstrated positive correlation of germinal to cortical matrix with external intraocular diameter ratio.
  • Identified key fissures (interhemispheric, parietooccipital, sylvian) by 22 weeks gestation.
  • Documented decreasing apparent diffusion coefficient (ADC) values in both grey and white matter with advancing gestational age.

Conclusions:

  • MRI is a reliable tool for evaluating fetal brain maturation during pregnancy.
  • Provides detailed insights into the spatiotemporal development of the fetal brain.
  • Supports the use of MRI in monitoring normal and potentially abnormal fetal brain development.