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From cat scratch disease to endocarditis, the possible natural history of Bartonella henselae infection
Frédérique Gouriet1, Hubert Lepidi, Gilbert Habib
1Unité des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine, Université de la Méditerranée, Marseille cedex 05, France. frederique.gouriet@medecine.univ-mrs.fr <frederique.gouriet@medecine.univ-mrs.fr>
Insights
Cat scratch disease (CSD) may precede infectious endocarditis (IE) in patients with heart valve lesions. This case highlights Bartonella henselae as a cause for both conditions, suggesting a potential progression from CSD to IE.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Infectious endocarditis (IE) caused by Bartonella henselae typically occurs in individuals with prior heart valve issues and cat exposure.
- Previously, no reported IE cases linked to Bartonella henselae involved a history of cat scratch disease (CSD).
Observation:
- This report details a patient who developed mitral valve IE due to Bartonella henselae six months after experiencing CSD.
Findings:
- The case presents a unique instance of Bartonella henselae infection progressing from CSD to IE.
- This suggests CSD might represent the initial infection phase of Bartonella henselae.
Implications:
- The findings suggest that patients with pre-existing heart valve lesions who contract CSD may be at risk for developing IE.
- This unique presentation deepens our understanding of Bartonella henselae pathogenesis and IE development.
Background:
Most patients with infectious endocarditis (IE) due to Bartonella henselae have a history of exposure to cats and pre-existing heart valve lesions. To date, none of the reported patients have had a history of typical cat scratch disease (CSD) which is also a manifestation of infection with B. henselae.
Case Presentation:
Here we report the case of a patient who had CSD and six months later developed IE of the mitral valve caused by B. henselae.
Conclusion:
Based on this unique case, we speculate that CSD represents the primary-infection of B. henselae and that IE follows in patients with heart valve lesions.
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