From cat scratch disease to endocarditis, the possible natural history of Bartonella henselae infection
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Published on: August 31, 2013
Frédérique Gouriet1, Hubert Lepidi, Gilbert Habib
1Unité des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine, Université de la Méditerranée, Marseille cedex 05, France. frederique.gouriet@medecine.univ-mrs.fr <frederique.gouriet@medecine.univ-mrs.fr>
Insights
Cat scratch disease (CSD) may precede infectious endocarditis (IE) in patients with heart valve lesions. This case highlights Bartonella henselae as a cause for both conditions, suggesting a potential progression from CSD to IE.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Infectious endocarditis (IE) caused by Bartonella henselae typically occurs in individuals with prior heart valve issues and cat exposure.
- Previously, no reported IE cases linked to Bartonella henselae involved a history of cat scratch disease (CSD).
Observation:
- This report details a patient who developed mitral valve IE due to Bartonella henselae six months after experiencing CSD.
Findings:
- The case presents a unique instance of Bartonella henselae infection progressing from CSD to IE.
- This suggests CSD might represent the initial infection phase of Bartonella henselae.
Implications:
- The findings suggest that patients with pre-existing heart valve lesions who contract CSD may be at risk for developing IE.
- This unique presentation deepens our understanding of Bartonella henselae pathogenesis and IE development.
Background:
Most patients with infectious endocarditis (IE) due to Bartonella henselae have a history of exposure to cats and pre-existing heart valve lesions. To date, none of the reported patients have had a history of typical cat scratch disease (CSD) which is also a manifestation of infection with B. henselae.
Case Presentation:
Here we report the case of a patient who had CSD and six months later developed IE of the mitral valve caused by B. henselae.
Conclusion:
Based on this unique case, we speculate that CSD represents the primary-infection of B. henselae and that IE follows in patients with heart valve lesions.
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