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Memory and executive functioning in obsessive-compulsive disorder: a selective review.

Amanda Olley1, Gin Malhi, Perminder Sachdev

  • 1School of Psychiatry, University of New South Wales, Sydney, Australia. amanda.olley@sesiahs.health.nsw.gov.au

Journal of Affective Disorders
|April 20, 2007
PubMed
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Obsessive-compulsive disorder (OCD) is linked to executive dysfunction, affecting memory and decision-making. Further research into cognitive deficits in OCD is needed to understand its underlying causes.

Area of Science:

  • Neuropsychology
  • Cognitive Science
  • Psychiatry

Background:

  • Neurocognitive deficits in obsessive-compulsive disorder (OCD) remain incompletely understood.
  • This review focuses on memory and executive functioning in OCD.
  • Challenges in OCD neuropsychological research are examined.

Purpose of the Study:

  • To review neuropsychological findings in memory and executive functioning in OCD.
  • To identify challenges in OCD neuropsychological research.
  • To explore decision-making as a potential area of cognitive dysfunction in OCD.

Main Methods:

  • A selective review of the neuropsychological literature on OCD was conducted.
  • Databases searched included MEDLINE.
  • Literature known to the authors was also included.

Related Experiment Videos

Main Results:

  • The primary neuropsychological deficit in OCD appears to be executive dysfunction.
  • Memory deficits in OCD may be secondary to executive failures in encoding strategies.
  • Patients with OCD show slower response times, response perseveration, and difficulty adapting to change.

Conclusions:

  • Decision-making has received limited attention in OCD neuropsychological research despite its clinical relevance.
  • Decision-making deficits are a potential area of dysfunction in OCD.
  • Further investigation into decision-making may enhance understanding of OCD pathophysiology.