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Updated: Jul 15, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
[Twiddler's syndrome in a left pectoral implanted defibrillator]
S S Leyendecker1, F Reuter, C Steffens
1Chirurgische Klinik, St. Josef Hospital, Klinikum der Ruhruniversität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany. sirileyendecker@gmx.de
Twiddler's syndrome is a rare complication where pacemaker/defibrillator generators rotate in their pocket. Proper fixation is crucial, especially in patients with loose fatty tissue, to prevent lead dislodgement.
Area of Science:
- Cardiology
- Medical Devices
- Surgical Complications
Background:
- Twiddler's syndrome is a rare but significant complication post-pacemaker or defibrillator implantation.
- It involves spontaneous rotation of the implanted device generator within the subpectoral pocket.
- This rotation can lead to lead dislodgement and device malfunction.
Observation:
- A case of a 78-year-old man presenting with exit block 7 months after defibrillator implantation is detailed.
- The cause was identified as a 15-fold rotation of the defibrillator generator around its axis.
- This rotation resulted in the dislocation of the defibrillator's electrode.
Findings:
- The study verified generator rotation as the cause of the exit block.
- Dislocation of the defibrillator electrode was a direct consequence of the generator's rotation.
- The patient experienced a device malfunction due to lead displacement.
Implications:
- Secure fixation of pacemaker/defibrillator electrodes and generators is critical for preventing Twiddler's syndrome.
- Particular attention should be paid to patients with loose subcutaneous fatty tissue.
- Preventing this rare complication ensures device longevity and patient safety.
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