Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recompression and adjunctive therapy for decompression illness.

M H Bennett1, J P Lehm, S J Mitchell

  • 1Prince of Wales Hospital, Diving and Hyperbaric Medicine, Barker Street, Randwick, NSW, Australia, 2031. m.bennett@unsw.edu.au

The Cochrane Database of Systematic Reviews
|April 20, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ease and comfort of pre-oxygenation with high-flow nasal oxygen cannulae vs. facemask: a randomised controlled trial.

Anaesthesia·2022
Same author

A retrospective audit of postoperative days alive and out of hospital, including before and after implementation of the WHO surgical safety checklist.

Anaesthesia·2021
Same author

A toolbox for the longitudinal assessment of healthspan in aging mice.

Nature protocols·2020
Same author

Haemodynamic profiles of etomidate vs propofol for induction of anaesthesia: a randomised controlled trial in patients undergoing cardiac surgery.

British journal of anaesthesia·2019
Same author

The incidence of hyperthermia during craniotomy.

Anaesthesia and intensive care·2018
Same author

Complications of anaesthesia.

Anaesthesia·2018
Same journal

Interventions to prevent or cease electronic cigarette use in children and adolescents.

The Cochrane database of systematic reviews·2026
Same journal

Drugs to improve anaemia, quality of life, and physical function in people with myelodysplastic syndromes (MDS).

The Cochrane database of systematic reviews·2026
Same journal

Interventions for smoking cessation in inpatient psychiatry settings.

The Cochrane database of systematic reviews·2026
Same journal

Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.

The Cochrane database of systematic reviews·2026
Same journal

Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.

The Cochrane database of systematic reviews·2026
Same journal

Views and experiences of weight management for people living with mobility‑limiting conditions, intellectual disabilities or severe mental illness: a qualitative evidence synthesis.

The Cochrane database of systematic reviews·2026
See all related articles

Recompression therapy is standard for treating decompression illness (DCI), but evidence from randomized trials is lacking. Adjunctive therapies like NSAIDs or heliox may reduce recompression frequency but do not improve recovery odds.

Area of Science:

  • Hyperbaric medicine
  • Diving physiology
  • Emergency medicine

Background:

  • Decompression illness (DCI) arises from bubble formation after breathing compressed gas.
  • DCI can range from mild symptoms to severe outcomes like paralysis or death.
  • Recompression is the established treatment, with strategies explored for delayed treatment.

Purpose of the Study:

  • To evaluate the effectiveness and safety of recompression and adjunctive therapies for DCI.
  • To synthesize evidence from randomized controlled trials on DCI treatment strategies.

Main Methods:

  • Searched multiple databases (CENTRAL, MEDLINE, CINAHL, EMBASE) and hyperbaric medicine literature.
  • Included randomized controlled trials comparing recompression schedules or adjunctive therapies against standard treatment.

Related Experiment Videos

  • Extracted data independently, assessed internal validity, and resolved discrepancies.

    • Main Results:

    • Two randomized controlled trials met inclusion criteria; data pooling was not feasible.
    • Non-steroidal anti-inflammatory drugs (NSAIDs) did not improve DCI recovery but reduced recompression frequency.
    • Helium-oxygen (heliox) breathing tables showed lower odds of multiple recompressions compared to oxygen tables.

    Conclusions:

    • Recompression therapy lacks robust randomized controlled trial evidence.
    • NSAIDs and heliox may decrease recompression frequency, but not improve recovery outcomes.
    • Further large, rigorous trials are needed to clarify benefits of different breathing gases and pressure profiles in recompression therapy.