Related Experiment Videos
[Polymorphism of five X-STR loci in Chinese Achang ethnic group]
Shan-Zhi Gu1, Jing-Fang Zhong, Zhi-Qiang Mu
1The Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University, Xi'an 710061, China.
Objective:
To investigate the genetic polymorphism and applied value in forensic medicine of five short tandem repeats (STRs) loci(DXS7130, DXS7132, DXS7133, DXS6804 and DXS8378) on X-chromosome in Achang ethnic group.
Methods:
Allele frequency and genotype distribution of five X-STR loci among 100 unrelated individuals from Achang ethnic group were analyzed by PCR following polyacrylamide gel electrophoresis and silver staining. Hardy-Weinberg equilibrium of females was tested and forensic parameters were calculated.
Result:
All the five STR loci were polymorphic in Achang ethnic group. Chi-square test indicated that genotype distribution of females was in accordance with Hardy-Weinberg equilibrium.
Conclusion:
These results enrich Chinese genetic database and can be applied to individual identification, paternity testing and population genetics.
Related Concept Videos
Single Nucleotide Polymorphisms-SNPs
Genetic Lingo
Pleiotropy
Polygenic Traits
Polygenic Traits
Dihybrid Crosses