What is a suggestion? The neuroscience of implicit processing heuristics in therapeutic hypnosis and psychotherapy

Neuroscience and bioinformatics research on activity-dependent gene expression and brain plasticity in memory and learning are used to reconceptualize a fundamental question of therapeutic hypnosis, "What is a suggestion?" John Kihlstrom's cognitive-behavioral perspective of implicit (unconscious) and explicit (conscious) memory and Eric Kandel's Nobel Prize winning neurobiological research are integrated for a 30-year update of Milton H. Erickson's "neuro-psycho-physiology" of therapeutic hypnosis. Implicit processing heuristics are proposed as a more general framework for Erickson's concept of permissive indirect suggestions in therapeutic hypnosis and psychotherapy. These perspectives are illustrated by utilizing implicit processing heuristics to facilitate the four-stage creative process in converting implicit to explicit memory in a brain-damaged patient.