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Related Experiment Video

Updated: Jul 15, 2026

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

Transplantation from non-heart-beating donors.

M Rela¹, W Jassem

¹Liver Transplant Unit, Institute of Liver Studies, King's College Hospital, Denmark Hill, London, United Kingdom. mohamed.rela@kcl.ac.uk

Transplantation Proceedings

|April 21, 2007

Summary

Non-heart-beating donor (NHBD) transplants are being used more due to organ shortages. Recent data show promising outcomes, increasing interest in this donor source for organ transplantation.

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Area of Science:

Organ transplantation research
Nephrology and Urology
Surgical innovation

Background:

Increasing organ transplant waiting lists necessitate expanded donor pools.
Static cadaver organ donor numbers limit transplantation rates.
Non-heart-beating donor (NHBD) programs offer a potential solution.

Purpose of the Study:

To review recent advancements and outcomes in NHBD transplantation.
To assess the viability of NHBD programs utilizing Maastricht criteria.
To highlight the growing interest in utilizing NHBDs for organ recovery.

Main Methods:

Review of recent clinical reports and data on NHBD programs.
Focus on NHBDs meeting Maastricht category 3 criteria.
Synthesis of current evidence on NHBD transplant outcomes.

Main Results:

NHBD transplants have been successfully reintroduced into clinical practice.
Programs using Maastricht category 3 criteria show encouraging outcomes.
The data suggest a growing interest and potential for NHBD organ donation.

Conclusions:

NHBD transplantation is a viable option to address organ shortages.
Continued research and program development are warranted for NHBDs.
NHBDs represent a valuable, underutilized donor pool for transplantation.