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Updated: Jul 15, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
10:13

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

New tensio-active molecules stabilize a human G protein-coupled receptor in solution

Marjorie Damian1, Sandrine Perino, Ange Polidori

  • 1Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-Universités Montpellier I et II, Faculté de Pharmacie, 15 Av. Ch. Flahault, BP 14491, 34093 Montpellier Cedex 5, France.

FEBS Letters
|April 21, 2007
PubMed
Summary

New phospholipid-like surfactants stabilize the G protein-coupled receptor BLT1, overcoming challenges in membrane protein structural characterization. These novel compounds offer enhanced stability compared to traditional detergents.

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