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Updated: Jul 15, 2026

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

Therapeutic apheresis for myositises

Véronique Le Guern1, Loïc Guillevin

  • 1Service de Médecine Interne, Hôpital Cochin, AP-HP, Université de Paris - René-Descartes, 27, rue du faubourg Saint-Jacques, 75689 Paris Cedex 14, France.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|April 21, 2007
PubMed

The inflammatory myopathies, commonly described as idiopathic, are the largest group of acquired and potentially treatable myopathies. Dermatomyositis and polymyositis are generally responsive to immunosuppressive therapies, but could be refractory to them. Therapeutic plasma exchanges (TPE) have been used for three decades to treat autoimmune diseases. Their mechanism of action, which hinges on profound modulation of the immune system, is only partially understood. Despite the absence of supportive evidence provided by controlled trials, some observations suggest that TPE could have a role to play in the therapeutic strategy for refractory inflammatory myopathies, especially acute forms. TPE should probably be indicated preferentially for refractory and acute inflammatory myopathies, in combination with immunosuppression and/or anti-B-lymphocyte therapy.

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