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Related Experiment Videos

Pulmonary involvement in Behçet's disease.

Oğuz Uzun1, Levent Erkan, Ilkser Akpolat

  • 1Department of Pulmonary Medicine, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. oguzuzun67@yahoo.com.tr

Respiration; International Review of Thoracic Diseases
|April 21, 2007
PubMed
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Pulmonary involvement in Behçet's disease (BD) indicates poor prognosis. This study highlights pulmonary artery thrombosis and vasculitis in BD, recommending specific diagnostic and treatment approaches for better patient outcomes.

Area of Science:

  • Rheumatology
  • Cardiology
  • Pulmonology

Background:

  • Behçet's disease (BD) is a multisystem vasculitis.
  • Pulmonary involvement in BD is associated with poor prognosis and high mortality.

Purpose of the Study:

  • To report on patients with BD and pulmonary involvement.
  • To discuss pulmonary artery thrombus and small-sized vasculitis in BD.

Main Methods:

  • Study included fifteen patients with BD and pulmonary involvement.
  • Massive hemoptysis was observed in all patients with pulmonary artery aneurysm (PAA).

Main Results:

  • Eleven patients had macroscopic pulmonary vascular disease (PAA, thrombi, or both).
  • Three patients had microscopic pulmonary vascular disease.

Related Experiment Videos

  • One patient had pulmonary cryptococcosis.

    • Conclusions:

    • Pulmonary vasculitis in BD involves macroscopic and microscopic disease.
    • Pulmonary artery thrombosis is a key finding, distinct from pulmonary emboli.
    • Spiral CT angiography is optimal for diagnosis; treatment varies by vascular disease type.