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[Cutaneous leishmaniasis].

E von Stebut1, C Sunderkötter

  • 1Universitäts-Hautklinik Mainz, 55131, Mainz. onstebu@mail.uni-mainz.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|April 21, 2007
PubMed
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Leishmaniasis infections are rising globally due to travel, presenting diverse clinical forms like cutaneous leishmaniasis. Early diagnosis and appropriate treatment, including newer options like miltefosine, are crucial for managing this neglected tropical disease.

Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Dermatology

Context:

  • Global increase in Leishmania infections driven by international travel.
  • Central Europe experiencing a rise in imported leishmaniasis cases.
  • Leishmaniasis manifestations vary based on species and host immunity.

Purpose:

  • To outline the epidemiology, clinical presentations, and diagnostic approaches for leishmaniasis.
  • To discuss differential diagnoses and therapeutic strategies for cutaneous and mucocutaneous leishmaniasis.
  • To highlight emerging treatment options and their significance.

Summary:

  • Leishmaniasis presents in various forms (cutaneous, mucocutaneous, visceral) following travel to endemic areas.
  • Diagnosis relies on clinical suspicion, travel history, and laboratory confirmation (smear, biopsy, culture).

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  • Treatment ranges from topical to systemic therapies, with miltefosine offering a less toxic alternative.

    • Impact:

    • Improved awareness of leishmaniasis risk factors associated with global travel.
    • Enhanced diagnostic capabilities and timely initiation of appropriate patient management.
    • Potential for improved patient outcomes with the adoption of newer, safer therapeutic agents.