Evaluation of tissue discards after implementation of anti-HBc test in a tissue bank in Spain
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Published on: March 13, 2015
Rafael Villalba1, Gema Fornés, Marcela Eisman
1Centro Regional de Transfusión Sanguínea y Banco Sectorial de Tejidos, Avda. San Alberto Magno s/n, 14004, Cordoba, Spain. rafael.villalba.sspa@juntadeandalucia.es
Abstract:
The recent introduction as a minimum test required in The Guide to Safety and Quality Assurance for Organs, Tissues and Cells (Council Europe) and the Directive 2004/23/EC applied to donation, procurement, testing, processing, preservation, storage and distribution of human cells and tissues make necessary the implementation of these markers in all European Tissue Establishments. In this study we have analyzed the impact in tissues discard by introducing anti-HBc in a European Tissue Establishment in a country with a high prevalence of HBV infection. The adoption of this exclusion criteria in this region results in acceptably rejection rates among tissue donors, although some studies are needed on basis a risk assessment to determine the eligibility for clinical use.
