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Two cases of interathoracic pathologies presented as secondory hypertrophic osteoarthopathy
1Department of Radiology, Addis Ababa University, Ethiopia.
Ethiopian Medical Journal
|April 24, 2007
Summary
Hypertrophic osteoarthropathy often links to lung cancer and benign tumors. This study presents two cases, highlighting the association between intrathoracic masses and this bone disorder.
Area of Science:
- Oncology
- Rheumatology
- Pulmonology
Background:
- Hypertrophic osteoarthropathy (HO) is a clinical syndrome characterized by specific joint and bone abnormalities.
- Intrathoracic neoplasms, particularly lung cancers, are the most common underlying cause of secondary HO.
Observation:
- Two distinct cases of secondary HO are presented: a 50-year-old male with bronchogenic carcinoma and a 44-year-old female with a benign pleural fibroma.
- Both patients exhibited symptoms including weight loss, chest discomfort, and joint pain, with imaging suggestive of intrathoracic masses and HO.
Findings:
- Diagnostic investigations, including bronchoscopy with biopsy, confirmed bronchogenic carcinoma in the first patient.
- Surgical intervention and subsequent biopsy revealed a benign pleural fibroma in the second patient.
Implications:
- These cases underscore the importance of investigating intrathoracic pathologies in patients presenting with symptoms suggestive of hypertrophic osteoarthropathy.
- Early diagnosis and management of underlying neoplasms, whether malignant or benign, are crucial for addressing HO.
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