Related Experiment Video
Updated: Jul 15, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
[More potential organ donors than actual donations in 52 intensive-care units in the Netherlands, 2001-2004]
N E Jansen1, H A van Leiden, M H Sieber-Rasch
1Nederlandse Transplantatie Stichting, Postbus 2304, 2301 CH Leiden. n.jansen@transplantiestichting.nl
Objective:
To assess the number of potential organ donors and the main reasons why organ donation is not performed.
Design:
Retrospective.
Method:
The number of potential heart-beating (HB) and non-heart-beating (NHB) donors was assessed by reviewing the medical records of 588o patients who died between 2001 and 2004 in 52 intensive-care units (ICUs) in 30 hospitals. The number of actual donations was also assessed.
Results:
The potential of HB donors was 2.5 to possibly 6.6% of all ICU deaths and HB donation was performed in 1.9% of all ICU deaths. The potential of NHB donors of category III was at least 4.2% of all ICU deaths and NHB donation was performed in 1.0% of all ICU deaths. The main difficulty in the donation process was objection from family members, which was reported in 45% of all potential HB and NHB donors and in 59% of all donation requests to relatives. Of the potential HB and NHB donors 7.3% were not identified as potential donors.
Conclusion:
These results confirm that organ-donor potential is greater than the number of actual donations. Objection from family members is the main limiting factor.
Related Concept Videos
Kidney Transplant I: Introduction
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure

