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Related Experiment Videos

Risk for recurrence in depression.

Stephanie L Burcusa1, William G Iacono

  • 1Department of Psychology, University of Minnesota, N218 Elliott Hall, 75 East River Road, Minneapolis, MN 55455, USA.

Clinical Psychology Review
|April 24, 2007
PubMed
Summary
This summary is machine-generated.

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Recurrent depression is often linked to an underlying genetic vulnerability. This vulnerability may also increase susceptibility to psychosocial risk factors and subsequent depressive episodes.

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Genetics

Background:

  • Depression is a highly recurrent disorder with substantial personal and public health impacts.
  • Preventing depressive episodes recurrence is crucial, necessitating identification of specific recurrence risk factors.
  • Risk factors for recurrent depression may differ from those for first-onset depression.

Purpose of the Study:

  • To review and synthesize research on risk factors specific to the recurrence of depression.
  • To evaluate the role of demographic, clinical, familial, psychosocial, and psychological variables in recurrent depression.
  • To assess the explanatory power of scar theories in linking these risk factors to recurrent depression.

Main Methods:

  • Systematic review of studies identifying risk factors for depression recurrence.

Related Experiment Videos

  • Analysis of demographic, clinical, family history, psychosocial, and psychological variables.
  • Evaluation of scar theories to explain the link between risk factors and recurrent depression.

    • Main Results:

    • Identified demographic factors (gender, SES, marital status), clinical factors (age at onset, episode count, severity, comorbidity), family history, and psychosocial/psychological factors (functioning, cognitions, personality, support, life events) associated with recurrence.
    • Scar theories offer a potential framework for understanding these associations.
    • Recurrent depression appears linked to an inherent vulnerability, potentially genetic.

    Conclusions:

    • Recurrent depression is associated with an underlying vulnerability, likely with a significant genetic component.
    • This genetic vulnerability may predispose individuals to both recurrent depressive episodes and associated psychosocial risk factors.
    • Further research is needed to elucidate the complex interplay between genetic predisposition and environmental factors in recurrent depression.