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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
mTOR Signaling and Cancer Progression03:03

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The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
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Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Related Experiment Video

Updated: Jul 15, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

[Breast cancer in men].

Mohamed Issam Beyrouti1, Rahma Beyrouti, Ramez Beyrouti

  • 1Service de Chirurgie Générale, EPS Habib Bourguiba, Sfax, Tunisia. beyroutimi@yahoo.fr

Presse Medicale (Paris, France : 1983)
|April 24, 2007
PubMed
Summary

Male breast cancer is rare, often diagnosed late, and linked to hormone imbalances. Early detection is crucial for better outcomes in this uncommon cancer.

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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Area of Science:

  • Oncology
  • Endocrinology

Background:

  • Male breast cancer is a rare condition, typically affecting men over 60.
  • Late-stage diagnosis is common, leading to a poorer prognosis despite men's limited breast tissue.
  • Hormonal imbalances, specifically elevated estrogen or prolactin, are implicated in its development.

Purpose of the Study:

  • To review the characteristics, diagnosis, and treatment of male breast cancer.
  • To highlight the challenges in early detection and the impact of late diagnosis on prognosis.
  • To discuss the role of hormone receptors and treatment modalities in male breast cancer.

Main Methods:

  • Review of clinical presentation, diagnostic methods (clinical exam, ultrasonography, mammography, cytology, biopsy).
  • Analysis of pathological findings, including common cancer types (infiltrating ductal carcinoma) and lymph node involvement.
  • Examination of treatment strategies: surgery (modified radical mastectomy), radiotherapy, hormone therapy, and chemotherapy.

Main Results:

  • Infiltrating ductal carcinoma comprises 70-90% of male breast cancers.
  • Lymph node spread occurs in 50-75% of cases.
  • Tumors frequently express progesterone and estrogen receptors, more so than in women.

Conclusions:

  • Male breast cancer diagnosis is often delayed, impacting prognosis.
  • Hormone therapy is a primary treatment, with chemotherapy reserved for specific cases.
  • Effective management requires a multidisciplinary approach, considering hormonal status and disease stage.