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Bridged androstenediol analogs as ER-beta selective SERMs.

Timothy A Blizzard1, Candido Gude, Wanda Chan

  • 1Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA. tim_blizzard@merck.com

Bioorganic & Medicinal Chemistry Letters
|April 24, 2007
PubMed
Summary

Researchers synthesized bridged androstenediol derivatives. These novel compounds showed decreased selectivity for estrogen receptor beta compared to non-bridged versions.

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