Related Experiment Video
Updated: Jul 15, 2026

Modification of the Treatment Methods for Wasting Marmoset Syndrome with Tranexamic Acid and Supportive Measures
Published on: July 12, 2024
Treating severe acute malnutrition seriously
1Centre for International Health and Development and Valid International Ltd, Unit 14 Standingford House, 26 Cave Street, Oxford OX4 1BA, UK. steve@validinternational.org
Insights
Community-based therapeutic care (CTC) significantly reduces child deaths from severe acute malnutrition (SAM). This approach increases treatment access and recovery rates, proving cost-effective for child survival programs.
Area of Science:
- Public Health
- Pediatrics
- Nutrition Science
Background:
- Severe acute malnutrition (SAM) impacts 13 million children globally, causing 1-2 million preventable deaths annually.
- High case fatality rates (20-30%) persist in hospitals treating SAM, with limited access to care.
- Existing treatment models struggle to reach a significant proportion of affected children.
Purpose of the Study:
- To evaluate the effectiveness of community-based therapeutic care (CTC) programs in managing SAM.
- To assess the impact of CTC on case fatality rates and treatment coverage.
- To determine the cost-effectiveness of integrating CTC into child survival initiatives.
Main Methods:
- Implementing community-based therapeutic care (CTC) programs utilizing ready-to-use therapeutic foods.
- Focusing on outpatient treatment for the majority of SAM cases.
- Promoting early presentation and compliance through accessible services.
Main Results:
- CTC programs have dramatically reduced case fatality rates for SAM.
- Significant increases in the number of children accessing and completing treatment have been observed.
- Initial data suggest CTC is a cost-effective intervention.
Conclusions:
- Community-based therapeutic care (CTC) offers a highly effective strategy for reducing mortality in children with SAM.
- CTC improves access to care and recovery rates, addressing limitations of traditional hospital-based treatment.
- Integration of CTC into mainstream child survival programs is recommended for greater public health impact.
Abstract:
Severe acute malnutrition (SAM) affects approximately 13 million children under the age of 5 and is associated with 1-2 million preventable child deaths each year. In most developing countries, case fatality rates (CFRs) in hospitals treating SAM remain at 20-30% and few of those requiring care actually access treatment. Recently, community-based therapeutic care (CTC) programmes treating most cases of SAM solely as outpatients have dramatically reduced CFRs and increased the numbers receiving care. CTC uses ready-to-use therapeutic foods and aims to increase access to services, promoting early presentation and compliance, thereby increasing coverage and recovery rates. Initial data indicate that this combination of centre-based and community-based care is cost effective and should be integrated into mainstream child survival programmes.
Related Concept Videos
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Acute Pancreatitis II: Clinical Manifestations and Management
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Acute Kidney Injury V: Interprofessional Care
Acute Pyelonephritis II: Diagnostic Studies and Management