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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Clinical outcome of urgent coronary artery bypass grafting
Do-Kyun Kim1, Kyung-Jong Yoo, You Sun Hong
1Department of Thoracic and Cardiovascular Surgery, Severance Hospital Cardiovascular Center, 134 Sinchon-dong, Seodaemun-gu, Seoul, Korea.
Insights
Urgent coronary artery bypass grafting (CABG) carries a high in-hospital mortality risk. However, patients who survive urgent CABG can achieve a favorable 10-year survival rate, highlighting the importance of prompt intervention.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Outcomes Research
Background:
- Urgent coronary artery bypass grafting (CABG) is associated with increased mortality compared to elective procedures.
- Prompt surgical revascularization is critical for patients with acute coronary conditions.
Purpose of the Study:
- To evaluate the clinical outcomes of patients undergoing urgent coronary artery bypass grafting (CABG).
- To identify preoperative risk factors associated with mortality in urgent CABG patients.
Main Methods:
- Retrospective analysis of 104 patients who underwent urgent CABG between July 1992 and May 2005.
- Comparison of preoperative characteristics and postoperative outcomes between survivors and non-survivors.
- Identification of independent risk factors for mortality using logistic regression.
Main Results:
- In-hospital mortality rate for urgent CABG was 17.3% (18/104), with low cardiac output being the most common cause of death.
- Independent preoperative risk factors for mortality included advanced age (>70 years), preoperative shock, and low ejection fraction (<40%).
- The 10-year actuarial survival rate for patients who underwent urgent CABG was 61%.
Conclusions:
- Despite a high operative mortality, urgent CABG can lead to favorable long-term outcomes for survivors.
- Early identification and management of risk factors are crucial for improving outcomes in urgent CABG patients.
Abstract:
Urgent coronary artery bypass grafting (CABG) has a higher mortality rate than elective CABG. The purpose of this study was to evaluate the clinical outcome of urgent CABG. From July 1992 to May 2005, 104 patients underwent urgent CABG. All patients required an urgent surgical revascularization within 24 hr of diagnostic coronary angiography. In-hospital mortality after urgent CABG was 17.3% (18/104). We compared preoperative characteristics and postoperative clinical outcomes between the survival group (n=86) and the mortality group (n=18). The mean age was 61.7 yr (range, 35-83). The most common cause of mortality was low cardiac output. The independent preoperative risk factors of mortality included advanced age (>70 yr) (OR=3.998, p=0.046), preoperative shock status (OR=6.542, p=0.011), and low ejection fraction (<40%) (OR=4.492, p=0.034). Other risk factors of mortality included prolonged cardiopulmonary bypass time, prolonged ventilator use, and extended intensive care unit stay. The 10-yr actuarial survival rate was 61%. Although the operative mortality rate was high after urgent CABG, a favorable long-term clinical outcome can be expected if the patients survive.
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