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Updated: Jul 15, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
Published on: December 15, 2023
Hepatitis B/C virus co-infection in Iran: a seroepidemiological study
Shahryar Semnani1, Gholamreza Roshandel, Nafiseh Abdolahi
1Department of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Golestan Research Center, Iran. sh_semnani@yahoo.com
Background/Aims:
As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.
Methods:
139 HBsAg-positive subjects were enrolled in the study. Serum samples were tested using ELISA method for anti-HCV antibodies. Chi-square and Fisher's exact tests were used to compare the proportions.
Results:
There were 68 (48.9%) males and 71 (51.1%) females. The mean age was 41.89+/-11.30 years. One case was excluded because of inadequate blood sampling. Anti-HCV antibody was positive in 17 (12.3%) of the 138 remaining subjects. Seropositivity of HCV was similar between female and male patients (p=0.69).
Conclusion:
The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).
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