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Related Concept Videos

Structure and Function of Platelets01:18

Structure and Function of Platelets

The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Formation of the Platelet Plug01:22

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

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Updated: Jul 15, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
09:49

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Published on: January 31, 2018

Guidelines for the transfusion of platelets.

A Bosly1, L Muylle, L Noens

  • 1Service d'Hématologie, Hôpital universitaire Mont-Godinne (UCL), Yvoir, Belgique.

Acta Clinica Belgica
|April 25, 2007
PubMed
Summary

New guidelines aim to standardize platelet transfusion practices in Belgium. These recommendations focus on rationalizing clinical indications and optimizing therapy for better patient outcomes.

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Area of Science:

  • Hematology
  • Transfusion Medicine
  • Clinical Guidelines

Background:

  • Current clinical indications for platelet transfusion lack standardization.
  • Variability exists in platelet concentrate quality and transfusion protocols.

Purpose of the Study:

  • To develop standardized and rationalized clinical indications for platelet transfusion in Belgium.
  • To establish guidelines for ideal platelet concentrate and optimal transfusion therapy.

Main Methods:

  • Convening an expert meeting organized by the Superior Health Council and the Belgian Hematological Society.
  • Discussion and consensus on indications, concentrate characteristics, and transfusion strategies.
  • Validation of expert recommendations by a working group.

Main Results:

  • Development of comprehensive recommendations for platelet transfusion.
  • Focus on harmonizing practices across Belgian hospitals.

Conclusions:

  • Standardized guidelines are crucial for rationalizing platelet transfusion.
  • Harmonized protocols will improve the safety and efficacy of platelet transfusion therapy.