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Related Experiment Video

Updated: Jul 15, 2026

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans

Published on: December 11, 2016

Early explosive force reduction associated with exercise-induced muscle damage.

D García-López¹, J A de Paz, R Jiménez-Jiménez

¹Department of Physiology, University of León, Campus Universitario, 24071 León, Spain.

Journal of Physiology and Biochemistry

|April 25, 2007

Summary

Eccentric exercise reduces explosive muscle force, impacting both squat jump (SJ) and countermovement jump (CMJ). Creatine kinase (CK) levels predict force loss better than muscle soreness.

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Induction and Assessment of Exertional Skeletal Muscle Damage in Humans

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Published on: December 11, 2016

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

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Published on: October 10, 2019

Area of Science:

Exercise Physiology
Muscle Damage Research

Background:

Eccentric exercise can induce muscle damage, leading to decreased muscle function.
Understanding the early markers of this damage is crucial for athletes and clinicians.

Purpose of the Study:

To analyze the loss of muscle explosive force after eccentric exercise.
To investigate the relationship between force loss, muscle soreness, and blood creatine kinase (CK) levels.

Main Methods:

Participants performed 120 eccentric knee extensor actions.
Squat jump (SJ) and countermovement jump (CMJ) heights were measured.
Muscle soreness and blood CK levels were assessed at multiple time points.

Main Results:

SJ and CMJ heights significantly decreased for at least 24 hours post-exercise.
Blood CK levels and muscle soreness increased significantly over time.
CK activity at 24 hours correlated with immediate and 6-hour SJ/CMJ height loss.

Conclusions:

Eccentric exercise impairs explosive force capacity in both SJ and CMJ.
Blood CK levels are a more reliable predictor of explosive force reduction than muscle soreness.