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Depression in Dhat syndrome.

Vikas Dhikav1, Neeraj Aggarwal2, Supriya Gupta2

  • 1All India Institute of Medical Sciences, New Delhi, India;.

The Journal of Sexual Medicine
|April 25, 2007
PubMed
Summary
This summary is machine-generated.

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Depression is common in Dhat syndrome, a culture-bound condition. Treatment with selective serotonin reuptake inhibitors (SSRIs) and counseling showed significant improvement in patients.

Area of Science:

  • Psychiatry
  • Cultural Psychiatry
  • Psychopharmacology

Background:

  • Dhat syndrome is a culture-bound condition prevalent in the Indian subcontinent, characterized by excessive preoccupation with semen loss.
  • Previous reports suggest an association between Dhat syndrome and depressive symptoms, necessitating further investigation into prevalence and quantification.

Purpose of the Study:

  • To determine the prevalence of depression in patients presenting with Dhat syndrome.
  • To quantify depressive features and assess the therapeutic response to fluoxetine in this population.

Main Methods:

  • A study was conducted on 30 patients with Dhat syndrome attending a tertiary care hospital's Psychiatry Outpatient Department.
  • Patients were evaluated for depression using the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria and the Hamilton Depression Rating Scale (HAM-D).

Related Experiment Videos

  • Eligible patients received fluoxetine (20-40 mg/day), with fortnightly follow-ups to assess therapeutic response using HAM-D.

    • Main Results:

    • Out of 30 patients (mean age 29 years), 66% met DSM-IV criteria for depression.
    • Comorbid conditions included premature ejaculation (33.3%) and erectile dysfunction (6.6%).
    • Patients demonstrated a statistically significant therapeutic response to fluoxetine treatment.

    Conclusions:

    • Depressive phenomenology meeting DSM-IV criteria is common in Dhat syndrome.
    • Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine, combined with regular counseling, appear effective in managing Dhat syndrome with comorbid depression.